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Function Of Glucose Transport Molecule Clarified By UCLA Researchers
Researchers at the David Geffen School of Medicine at UCLA have solved the structure of a class of proteins known as sodium glucose co-transporters (SGLTs), which pump glucose into cells. These transport proteins are used in the treatment of chronic diarrhea via oral rehydration therapy, saving the lives of millions of children each year. The solution of the SGLT structure will accelerate development of new drugs designed to treat patients with diabetes and cancer.
Medical News Today  –  Jul 5, 2008 1:00 PM [GMT]  ¦  comment?
found in Health: Diabetes
Drug Reverses Retardation In Mice
snydeq writes "Rapamycin, a medication doctors prescribe to transplant patients to prevent organ rejection, has been used to reverse learning disorders and mild retardation associated with TSC (tuberous sclerosis complex) in mice. Because the condition is linked to autism, scientists believe the drug may be used to treat learning disabilities and short-term memory deficits in all kinds of autism as well. The scientists chose rapamycin after they realized the drug regulates one of the same proteins that the TSC gene does, just in different parts of the body. 'What was surprising is that we could give rapamycin to adult mice and reverse their condition,' said neurobiologist Alcino Silva of the David Geffen School of Medicine at UCLA. 'We did not know... that this drug would be equally effective for the learning disabilities as it is for tissue rejection.' Rapamycin treatment leveled the playing field between normal and TSC mice in as little as three days."Read more of this story at Slashdot.
Slashdot  –  Jun 27, 2008 12:33 PM [GMT]  ¦  comment?
found in Technology: Science
How Pop Singer Lost 'graduate'
DAVID Geffen is a brilliant businessman, but he made one incredibly bad call early in his career. In her new autobiography, "Society's Child," pop singer Janis Ian reveals how Geffen and Hal Ray, her agents at William Morris, once presented her with...
New York Post  –  Jun 26, 2008 07:42 AM [GMT]  ¦  comment?
found in Entertainment: Celebrity Gossip
Bollywood does Tinseltown
Reliance Entertainment, part of an Indian conglomerate controlled by the telecommunications and finance mogul Anil Ambani, is in talks to finance Steven Spielberg and David Geffen in a new venture.
International Herald Tribune  –  Jun 23, 2008 12:43 PM [GMT]  ¦  comment?
found in Business